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Proceedings Paper

Monitoring of cerebral hemodynamics during open-heart surgery in children using near-infrared intensity-modulated spectroscopy
Author(s): Matthias Kohl-Bareis; Russell W. Watson; Gabriel Chow; Idris Roberts; David T. Delpy; Mark Cope
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Paper Abstract

Neurological impairments following cardiopulmonary bypass (CPB) during open heart surgery can result from microembolism and ischaemia. Here we present preliminary results from monitoring cerebral hemodynamics during CPB with near infrared intensity modulated spectroscopy. In particular, the study had two main objectives: (1) to monitor the oxy- and deoxy hemoglobin concentrations and their changes during the CPB surgery and (2) to monitor the transport scattering coefficient ((mu) s') of the brain especially during cooling and rewarming. A new method for the calculation of absolute absorption coefficients ((mu) a) was also tested. This method is based upon the monitoring of attenuation and phase changes that are induced by variations in absorption. These variations can be generated either by alterations in the tissue oxygenation or by injecting a dye (indocyanine green) into the CPB circuit. Absolute oxy- and deoxyhemoglobin concentrations and their changes during the CPB were calculated. The preliminary results suggest that cooling of the brain does not significantly alter (mu) s'.

Paper Details

Date Published: 18 August 1997
PDF: 9 pages
Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); doi: 10.1117/12.280272
Show Author Affiliations
Matthias Kohl-Bareis, Univ. College London (Germany)
Russell W. Watson, Univ. College London (United Kingdom)
Gabriel Chow, The Hospital for Sick Children (United Kingdom)
Idris Roberts, The Hospital for Sick Children (United Kingdom)
David T. Delpy, Univ. College London (United Kingdom)
Mark Cope, Univ. College London (United Kingdom)


Published in SPIE Proceedings Vol. 2979:
Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II
Britton Chance; Robert R. Alfano, Editor(s)

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