Share Email Print
cover

Proceedings Paper

Endoscopic optical coherence tomography
Author(s): Guillermo J. Tearney; Brett E. Bouma; Mark E. Brezinski; Stephen A. Boppart; Constantinos Pitris; James F. Southern; Eric A. Swanson; James G. Fujimoto
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Optical coherence tomography (OCT) is a recently developed optical imaging technique that uses low coherence interferometry to perform high resolution, cross-sectional imaging in biological systems. While in vitro studies have been performed to demonstrate the feasibility of performing optical biopsy in human tissues, key technologies must be developed to extend this technique to in vivo internal organ systems. These advances include improvements in image acquisition speed, and the development of an OCT compatible catheter-endoscope. A fast scanning OCT system has recently been constructed. This system employs a high power (200 mW) chromium doped forsterite laser as the low coherence source and a piezoelectric fiber stretcher to induce reference arm optical path length delay. The fast scanning system acquires OCT images with an acquisition rate of four images per second, an axial resolution of 15 micrometers, and a signal to noise ratio of 112 dB. When incorporated with the recently constructed OCT compatible catheter-endoscope, this system is capable of obtaining high resolution endoscopic diagnostic images of tissue microstructure in vivo.

Paper Details

Date Published: 18 August 1997
PDF: 4 pages
Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); doi: 10.1117/12.280212
Show Author Affiliations
Guillermo J. Tearney, Massachusetts Institute of Technology (United States)
Brett E. Bouma, Massachusetts Institute of Technology (United States)
Mark E. Brezinski, Massachusetts General Hospital (United States)
Stephen A. Boppart, Massachusetts Institute of Technology (United States)
Constantinos Pitris, Massachusetts Institute of Technology (United States)
James F. Southern, Massachusetts General Hospital (United States)
Eric A. Swanson, MIT Lincoln Lab. (United States)
James G. Fujimoto, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 2979:
Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II
Britton Chance; Robert R. Alfano, Editor(s)

© SPIE. Terms of Use
Back to Top