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Proceedings Paper

Sol gel-based fiber optic pH sensor
Author(s): Sheila A. Grant; Robert S. Glass
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Paper Abstract

We report here on the development of a sol-gel based fiber optic sensor to monitor local blood pH. These sensors are being developed for invasive medical applications; that is, they will be coaxially threaded through a catheter beyond an occlusion in the vascular system. The fiber optic pH sensor design was based on the immobilization of a pH sensitive dye, seminaphthorhodamine-1 carboxylate, onto the tip or surface of an optical fiber using the sol-gel method. The fiber optic pH sensor was tested in phosphate buffer saline and human whole blood using a miniature fluorimeter system. Linear responses were obtained in blood in the pH range 6.7 to 8.0, which demonstrates potential for use for in vivo sensing.

Paper Details

Date Published: 16 June 1997
PDF: 7 pages
Proc. SPIE 2976, Biomedical Sensing, Imaging, and Tracking Technologies II, (16 June 1997); doi: 10.1117/12.275514
Show Author Affiliations
Sheila A. Grant, Lawrence Livermore National Lab. (United States)
Robert S. Glass, Lawrence Livermore National Lab. (United States)


Published in SPIE Proceedings Vol. 2976:
Biomedical Sensing, Imaging, and Tracking Technologies II
Tuan Vo-Dinh; Robert A. Lieberman; Gerald G. Vurek; Abraham Katzir, Editor(s)

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