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Proceedings Paper

Morphological and histological changes on skin induced by 1540-nm laser radiation
Author(s): Alexei V. Lukashev; Valery P. Solovyev; Boris I. Denker; Vadimir I. Kaz'min
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Paper Abstract

The dose-response relationship for producing different grades of burns on skin produced by single Er-glass laser pulse were determined for energy densities within the range 0.5-35 J/cm2 and pulse duration 100 ns and 2.5 ms. The persistent lesions on skin were subdivided into four morphologically different groups vs. radiant exposure of laser pulses. Histological investigation were made at 1- and 3-days post-exposure. Different methods of tissue preparation were tried to obtain better contrast of laser induced changes in skin tissue. At the 1-day post-exposure we observed on the histological samples coagulation of surface tissue, epidermis and dermis of skin depending on radiant exposure. 3-days histological samples revealed tearing of tissue detrit and active epitalization of damaged tissue.

Paper Details

Date Published: 2 May 1997
PDF: 7 pages
Proc. SPIE 2974, Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment, (2 May 1997); doi: 10.1117/12.275252
Show Author Affiliations
Alexei V. Lukashev, General Physics Institute (United States)
Valery P. Solovyev, Institute of Biophysics (Russia)
Boris I. Denker, General Physics Institute (Russia)
Vadimir I. Kaz'min, Institute of Biophysics (Russia)

Published in SPIE Proceedings Vol. 2974:
Laser and Noncoherent Ocular Effects: Epidemiology, Prevention, and Treatment
Bruce E. Stuck; Michael Belkin M.D., Editor(s)

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