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Proceedings Paper

Cultured human cornea healing process after free-electron-laser ablation
Author(s): Jin-Hui Shen; Karen Margaret Joos; Debra J. Shetlar; Richard D. Robinson; Gurpreet K. Thind; Glenn S. Edwards; Denis M. O'Day
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Paper Abstract

The purpose of this study is to investigate the healing process in cultured human cornea after infrared Free Electron Laser ablation. Fresh human cadaver cornea was ablated using the Free Electron Laser at the amide II band peak (6.45 micrometers ). The cornea was then cultured in an incubator for 18 days. Haze development within the ablated area was monitored during culture. Histologic sections of the cornea showed complete re-epithelialization of the lased area, and ablation of the underlying Bowman's layer and stroma. The endothelium appeared unaffected. Cultured human corneas may provide useful information regarding the healing process following laser ablation.

Paper Details

Date Published: 26 May 1997
PDF: 6 pages
Proc. SPIE 2971, Ophthalmic Technologies VII, (26 May 1997); doi: 10.1117/12.275106
Show Author Affiliations
Jin-Hui Shen, Vanderbilt Univ. (United States)
Karen Margaret Joos, Vanderbilt Univ. (United States)
Debra J. Shetlar, Vanderbilt Univ. (United States)
Richard D. Robinson, Vanderbilt Univ. (United States)
Gurpreet K. Thind, Vanderbilt Univ. (United States)
Glenn S. Edwards, Vanderbilt Univ. (United States)
Denis M. O'Day, Vanderbilt Univ. (United States)


Published in SPIE Proceedings Vol. 2971:
Ophthalmic Technologies VII
Pascal O. Rol; Karen Margaret Joos; Fabrice Manns, Editor(s)

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