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Proceedings Paper

Comparison of the optical properties of human liver tissue and liver metastases and investigation of the dynamic temperature behavior of optical tissue properties
Author(s): Joerg-Peter Ritz; Andre Roggan; Dirk Albrecht; D. Schaedel; Christoph-Thomas Germer; Heinz-Johannes Buhr
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Paper Abstract

The knowledge of the optical properties of human tissue is indispensable for the understanding and optimal use of laser applications in medicine, especially for dosimetrical questions in laser-induced thermotherapy of liver metastases. In addition photothermal therapies have to consider the dynamic behavior of optical properties. In this study we evaluated the optical tissue properties of normal human liver tissue and of colorectal liver metastases. We used the double integrating sphere technique and the inverse Mont Carlo- simulation for evaluation of the optical properties. We were able to demonstrate significant differences between native and coagulated tissue as well as between normal and metastatic tissue. In the investigation of the dynamic temperature behavior of optical properties we could demonstrate that the coagulation rate cannot be described by a linear model.

Paper Details

Date Published: 22 May 1997
PDF: 7 pages
Proc. SPIE 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII, (22 May 1997); doi: 10.1117/12.275083
Show Author Affiliations
Joerg-Peter Ritz, Benjamin Franklin Medical Ctr./Freie Univ. Berlin (Germany)
Andre Roggan, Benjamin Franklin Medical Ctr./Freie Univ. Berlin (Germany)
Dirk Albrecht, Benjamin Franklin Medical Ctr./Freie Univ. Berlin (Germany)
D. Schaedel, Benjamin Franklin Medical Ctr./Freie Univ. Berlin (Germany)
Christoph-Thomas Germer, Benjamin Franklin Medical Ctr./Freie Univ. Berlin (Germany)
Heinz-Johannes Buhr, Benjamin Franklin Medical Ctr./Freie Univ. Berlin (Germany)


Published in SPIE Proceedings Vol. 2970:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII
R. Rox Anderson; Kenneth Eugene Bartels; Lawrence S. Bass; Kenton W. Gregory; David M. Harris; Harvey Lui; Reza S. Malek; Gerhard J. Mueller; Michail M. Pankratov; Aaron P. Perlmutter; Hans-Dieter Reidenbach; Lloyd P. Tate; Graham M. Watson; Harvey Lui; Lawrence S. Bass; R. Rox Anderson; David M. Harris; Michail M. Pankratov; Kenneth Eugene Bartels; Lloyd P. Tate; Gerhard J. Mueller; Hans-Dieter Reidenbach; Graham M. Watson; Reza S. Malek; Aaron P. Perlmutter, Editor(s)

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