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Proceedings Paper

Optothermal measurement of stratum corneum thickness and hydration-depth profile
Author(s): Peng Xiao; Robert E. Imhof
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Paper Abstract

Opto-thermal in-vivo measurements of stratum corneum hydration can now be evaluated to give hydration depth profiles from a mathematical model that incorporates both the surface hydration and the changes of hydration with depth beneath the surface. We now present an analysis of water diffusion in the stratum corneum that can be related to such measurements. The results are compared with measurements of changes of surface hydration and hydration gradient with depth in a stratum corneum stripping experiment. Surface hydration and hydration gradient information can also be combined to yield a measure of stratum corneum thickness, as illustrated with a measured thickness map of the volar forearm.

Paper Details

Date Published: 22 May 1997
PDF: 11 pages
Proc. SPIE 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII, (22 May 1997); doi: 10.1117/12.275055
Show Author Affiliations
Peng Xiao, South Bank Univ. (United Kingdom)
Robert E. Imhof, South Bank Univ. (United Kingdom)


Published in SPIE Proceedings Vol. 2970:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII
R. Rox Anderson; Harvey Lui; Michail M. Pankratov; Kenneth Eugene Bartels; Gerhard J. Mueller; Graham M. Watson; Reza S. Malek; Lawrence S. Bass; Lloyd P. Tate; Hans-Dieter Reidenbach; Kenneth Eugene Bartels; R. Rox Anderson; Lawrence S. Bass; Aaron P. Perlmutter; Kenton W. Gregory; David M. Harris; David M. Harris; Harvey Lui; Reza S. Malek; Gerhard J. Mueller; Michail M. Pankratov; Aaron P. Perlmutter; Hans-Dieter Reidenbach; Lloyd P. Tate; Graham M. Watson, Editor(s)

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