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Proceedings Paper

In-vivo investigations on interstitial Ho:YAG laser therapy
Author(s): Ronald Sroka; Aaron P. Perlmutter; T. Pongratz; Rolf Muschter
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Paper Abstract

Laser induced interstitial thermotherapy is a new minimally invasive procedure for the treatment of benign prostatic hyperplasia. In this study Ho:YAG laser induced lesions were investigated on liver, kidney and prostates of canines. While the dependency of the induced lesions on the energy/pulse at a constant mean power had been investigated on the liver, the dependency on the pulse duration was studied on the kidney. Additionally the dependency of the lesions induced on the total applied energy at optimized parameters had been determined in prostate tissue. In all experiments it could be demonstrated that interstitial pulsed Ho:YAG irradiation resulted in a cavity surrounded by a coagulation zone. The results show that changing the pulse duration by a factor of two or changing the energy/pulse at a constant mean power result in no significant alteration of the lesions sizes. These experimental findings may offer new treatment modalities with respect to interstitial laser therapy of BPH without damaging the urethra.

Paper Details

Date Published: 22 May 1997
PDF: 5 pages
Proc. SPIE 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII, (22 May 1997); doi: 10.1117/12.275026
Show Author Affiliations
Ronald Sroka, Laser-Forschungslabor/Univ. Muenchen (Germany)
Aaron P. Perlmutter, New York Hospital-Cornell Medical Ctr. (United States)
T. Pongratz, Laser-Forschungslabor/Univ. Muenchen (Germany)
Rolf Muschter, Laser-Forschungslabor/Univ. Muenchen (Germany)

Published in SPIE Proceedings Vol. 2970:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII
R. Rox Anderson; Harvey Lui; Michail M. Pankratov; Kenneth Eugene Bartels; Gerhard J. Mueller; Graham M. Watson; Reza S. Malek; Lawrence S. Bass; Lloyd P. Tate; Hans-Dieter Reidenbach; Kenneth Eugene Bartels; R. Rox Anderson; Lawrence S. Bass; Aaron P. Perlmutter; Kenton W. Gregory; David M. Harris; David M. Harris; Harvey Lui; Reza S. Malek; Gerhard J. Mueller; Michail M. Pankratov; Aaron P. Perlmutter; Hans-Dieter Reidenbach; Lloyd P. Tate; Graham M. Watson, Editor(s)

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