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Proceedings Paper

Effects of overlap and pass number in CO2 laser skin resurfacing: preliminary results of residual thermal damage, cell death, and wound healing
Author(s): E. Victor Ross M.D.; Robert D. Glatter M.D.; Daniella Duke; Joop M. Grevelink M.D.
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Paper Abstract

Newer carbon-dioxide laser systems incorporating short pulse and scanning technology have been used effectively to resurface the skin. Although scarring is rare, as the number of resurfacing cases has increased, some hypertrophic scarring has been observed. Previous dermabrasion and continuous wave (cw) carbon-dioxide studies suggest that depth of injury and/or thermal damage are important predictors of scarring for a given anatomic region. To determine if overlapping laser pulses/scans significantly altered wound healing, we examined residual thermal damage, cell death, and histologic and clinical wound healing in a farm pig. The Ultrapulse and SilkTouch systems were used with various radiant exposures, degrees of overlap, and numbers of passes. Thermal damage was assessed by histology, and dermal cell viability was measured with nitrotetrazolium blue staining. Presence or absence of clinical scarring was determined by noting textural change and loss of skin markings. We observed that thermal damage and cell death depth did not increase significantly with pass number; however, by double-pulsing or double-scanning sites, residual thermal damage and cell death depth were increased as much as 100% over areas without immediate overlap of laser impacts. Also, scarring was increased focally in areas with overlap. We conclude that immediate overlapping of carbon- dioxide laser pulses/scans is a significant risk factor in increasing thermal damage, cell death, and scarring.

Paper Details

Date Published: 22 May 1997
PDF: 11 pages
Proc. SPIE 2970, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII, (22 May 1997); doi: 10.1117/12.275020
Show Author Affiliations
E. Victor Ross M.D., Naval Medical Ctr. (United States)
Robert D. Glatter M.D., Massachusetts General Hospital (United States)
Daniella Duke, Massachusetts General Hospital (United States)
Joop M. Grevelink M.D., Massachusetts General Hospital (United States)


Published in SPIE Proceedings Vol. 2970:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VII
R. Rox Anderson M.D.; Harvey Lui M.D.; Michail M. Pankratov; Kenneth Eugene Bartels D.V.M.; Gerhard J. Mueller; Graham M. Watson M.D.; Reza S. Malek M.D.; Lawrence S. Bass M.D.; Lloyd P. Tate V.D.M.; Hans-Dieter Reidenbach; Kenneth Eugene Bartels D.V.M.; R. Rox Anderson M.D.; Lawrence S. Bass M.D.; Aaron P. Perlmutter M.D.; Kenton W. Gregory M.D.; David M. Harris; David M. Harris; Harvey Lui M.D.; Reza S. Malek M.D.; Gerhard J. Mueller; Michail M. Pankratov; Aaron P. Perlmutter M.D.; Hans-Dieter Reidenbach; Lloyd P. Tate V.D.M.; Graham M. Watson M.D., Editor(s)

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