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Proceedings Paper

DNA/europium ion interaction by matrix-assisted laser desorption time-of-flight mass spectrometry
Author(s): Stephanie Bourin; Daniel McStay; Paul Kong Thoo Lin; Gary Duncan; Jim Lomax
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Paper Abstract

The interaction of DNA and lanthanide ions using Matrix assisted laser desorption time of flight mass spectrometry. 2', 4', 6' hydroxy acetophenone was the matrix used, and Europium chloride was the lanthanide salt used to interact with Adenine and Guanine containing synthetic oligonucleotides. The MALDI analysis permitted the detection of DNA/Europium adducts and also provided information on the stoichiometry of the interaction.

Paper Details

Date Published: 22 May 1997
PDF: 8 pages
Proc. SPIE 2985, Ultrasensitive Biochemical Diagnostics II, (22 May 1997); doi: 10.1117/12.274343
Show Author Affiliations
Stephanie Bourin, Robert Gordon Univ. (United Kingdom)
Daniel McStay, Robert Gordon Univ. (United Kingdom)
Paul Kong Thoo Lin, Robert Gordon Univ. (United Kingdom)
Gary Duncan, Rowett Research Institute (United Kingdom)
Jim Lomax, Rowett Research Institute (United Kingdom)

Published in SPIE Proceedings Vol. 2985:
Ultrasensitive Biochemical Diagnostics II
Gerald E. Cohn; Gerald E. Cohn; Steven A. Soper, Editor(s)

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