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Proceedings Paper

CAD system for full-digital mammography and its evaluation
Author(s): Hidefumi Kobatake; Kenichi Okuno; Masayuki Murakami; Masamitsu Ishida; Hideya Takeo; Shigeru Nawano
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Paper Abstract

The purpose of this study is to develop a clinical intelligent workstation for computer-aided diagnosis (CAD) of breast cancer using full digital mammography. It consists of a clinical workstation and Fuji Computed Radiography 9000 System. New image processing methods to extract tumor masses and clustered microcalcifications have been developed and implemented in the CAD system. A new filter called Iris Filter has been developed to detect tumor candidates. It realizes reliable detection of tumor candidates regardless of their sizes and their contrast against their background on mammograms. And a new method based on mathematical morphology has been developed to detect microcalcifications. It is adaptive to the imaging conditions of mammograms. One thousand, two hundred and twelve CR images, which include 240 malignant tumors, were used to test the performance of the system. The sensitivity for malignant tumors was 90. 5% and the average number of false positives per image were only 1.3. The true positive detection rate for clustered microcalcifications was 89.2% and the average number of false positives per image were 0.36. The high true positive rates and the low false positive detection characterize the proposed fulldigital CAD system, which shows the possibility of practical application of computer aided diagnosis of breast cancer. Keywords: breast cancer, mammography, CAD, malignant tumors, microcalcijIcations, irisfilter. morphological processing

Paper Details

Date Published: 25 April 1997
PDF: 8 pages
Proc. SPIE 3034, Medical Imaging 1997: Image Processing, (25 April 1997); doi: 10.1117/12.274161
Show Author Affiliations
Hidefumi Kobatake, Tokyo Univ. of Agriculture & Technology (Japan)
Kenichi Okuno, Tokyo Univ. of Agriculture & Technology (Japan)
Masayuki Murakami, Fuji Photo Film Co. Ltd. (Japan)
Masamitsu Ishida, Fuji Photo Film Co. Ltd. (Japan)
Hideya Takeo, Fuji Photo Film Co. Ltd. (Japan)
Shigeru Nawano, National Cancer Ctr. (Japan)

Published in SPIE Proceedings Vol. 3034:
Medical Imaging 1997: Image Processing
Kenneth M. Hanson, Editor(s)

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