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Proceedings Paper

Toward retinal vessel parameterization
Author(s): Xiaohong Gao; Anil A. Bharath; Alun J. Hughes; Alice Stanton; Neil Chapman; Simon Thom
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Paper Abstract

The reliable measurement of retinal vessel geometry in ordinary red-free fundus photographs is a challenging issue. Quite apart from refractive effects which can distort absolute measures, the existence of the central light reflex poses some interesting problems in vessel modelling and segmentation. One aim of our research is to obtain subpixel vessel width precision from digitised retinal photographs. For this purpose, we require a reasonable physical and mathematical model for the vessel intensity profile. In this paper, we review physical principles behind the image formation, leading to a twin Gaussian model. We test 4 non-linear parametric models based on Gaussian forms. Some applications of this model-based approach are introduced, including the parametric detennination of vessel centre and the accurate determination of vessel width in typical noisy clinical images. Key Words : retinal imaging. non-linear parametric models, parametric image models, sub-pixel resolution

Paper Details

Date Published: 25 April 1997
PDF: 11 pages
Proc. SPIE 3034, Medical Imaging 1997: Image Processing, (25 April 1997); doi: 10.1117/12.274160
Show Author Affiliations
Xiaohong Gao, Imperial College of Science, Technology, and Medicine (United Kingdom)
Anil A. Bharath, Imperial College of Science, Technology, and Medicine (United Kingdom)
Alun J. Hughes, Imperial College of Science, Technology, and Medicine (United Kingdom)
Alice Stanton, Imperial College of Science, Technology, and Medicine (United Kingdom)
Neil Chapman, Imperial College of Science, Technology, and Medicine (United Kingdom)
Simon Thom, Imperial College of Science, Technology, and Medicine (United Kingdom)


Published in SPIE Proceedings Vol. 3034:
Medical Imaging 1997: Image Processing
Kenneth M. Hanson, Editor(s)

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