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Proceedings Paper

Autoradiographic-based phantoms for emission tomography
Author(s): Gene R. Gindi; Doug Dougherty; Ing-Tsung Hsiao; Anand Rangarajan
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Paper Abstract

In the development of reconstruction algorithms in emission computed tomography (ECT), digital phantoms designed to mimic the presumed spatial distribution of radionuclide activity in a human are extensively used. Given the low spatial resolution in ECT, it is usually presumed that a crude phantom, usually with a constant activity level within an anatomically derived region, is sufficiently realistic for testing. Here, we propose that phantoms may be improved by assigning biologically realistic patterns of activity in more precisely delineated regions. Animal autoradiography is proposed as a source of realistic activity and anatomy. We discus the basics of radiopharmaceutical autoradiography and discuss aspects of using such data for a brain phantom. A few crude simulations with brain phantoms derived from animal data are shown.

Paper Details

Date Published: 25 April 1997
PDF: 12 pages
Proc. SPIE 3034, Medical Imaging 1997: Image Processing, (25 April 1997); doi: 10.1117/12.274126
Show Author Affiliations
Gene R. Gindi, SUNY/Stony Brook (United States)
Doug Dougherty, SUNY/Stony Brook (United States)
Ing-Tsung Hsiao, SUNY/Stony Brook (United States)
Anand Rangarajan, Yale Univ. (United States)

Published in SPIE Proceedings Vol. 3034:
Medical Imaging 1997: Image Processing
Kenneth M. Hanson, Editor(s)

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