Share Email Print
cover

Proceedings Paper

Dynamic light-scattering study of gelatin and aggregation of gastric mucin
Author(s): Rama Bansil; Xingxiang Cao; K. Ramakrishnan Bhaskar; Jeffrey Thomas LaMont
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Dynamic light scattering studies show that concentration and pH play important roles in determining pig gastric mucin's (PGM) ability to aggregate and gel. At low concentrations, PGM macromolecules exist in solution predominantly in the form of monomers. At high concentrations, PGM macromolecules aggregate to form supra-macromolecular clusters. When the pH of the high concentration PGM solution is changed from 7.0 to 2.0, the system undergoes a sol-gel transition: from a solution of polydisperse aggregates to a gel. This pH and concentration dependent sol-gel transition of PGM solution may provide a mechanism for the mammalian stomach to protect itself against being digested by the gastric juice.

Paper Details

Date Published: 2 May 1997
PDF: 10 pages
Proc. SPIE 2982, Optical Diagnostics of Biological Fluids and Advanced Techniques in Analytical Cytology, (2 May 1997); doi: 10.1117/12.273605
Show Author Affiliations
Rama Bansil, Boston Univ. and Beth Israel Hospital (United States)
Xingxiang Cao, Boston Univ. and Beth Israel Hospital (United States)
K. Ramakrishnan Bhaskar, Boston Univ. and Beth Israel Hospital (United States)
Jeffrey Thomas LaMont, Boston Univ. and Beth Israel Hospital (United States)


Published in SPIE Proceedings Vol. 2982:
Optical Diagnostics of Biological Fluids and Advanced Techniques in Analytical Cytology
Robert C. Leif; Alexander V. Priezzhev; Toshimitsu Asakura; Robert C. Leif, Editor(s)

© SPIE. Terms of Use
Back to Top