Share Email Print

Proceedings Paper

Dipyridophenazine complexes of Ru(II): versatile optical sensors for small and large molecules
Author(s): Catherine J. Murphy; Rajesh B. Nair; Caroline E. Keller; Emily S. Teng; Charles Pollard
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Bis(phenanthroline)dipyridophenazineruthenium(II), [(Ru(phen)2dppz]2+, exhibits unusual optical properties compared to other derivatives of [Ru(bpy)3]2+. [Ru(phen)2dppz]2+ does not exhibit photoluminescence in water, but does emit brightly at approximately 610 nm in the presence of nonaqueous solvents or hydrated polymers like DNA and Nafion. We have observed this `light switch' effect upon binding [Ru(phen)2dppz]2+ to a protein with a hydrophobic pocket (chymotrypsin), suggesting that we may be able to develop optical probes of protein tertiary structure. We have also prepared derivatives of [Ru(phen)2dppz]2+ that have ancillary ligands other than phenanthroline, and find that these molecules change color upon exposure to small molecules; the environmental parameters we have been able to assess so far include Lewis acidity, the nature of hydrated counterions, polarity, and hydrogen-based donation ability.

Paper Details

Date Published: 7 May 1997
PDF: 6 pages
Proc. SPIE 2980, Advances in Fluorescence Sensing Technology III, (7 May 1997); doi: 10.1117/12.273551
Show Author Affiliations
Catherine J. Murphy, Univ. of South Carolina (United States)
Rajesh B. Nair, Univ. of South Carolina (United States)
Caroline E. Keller, Univ. of South Carolina (United States)
Emily S. Teng, Univ. of South Carolina (United States)
Charles Pollard, Univ. of South Carolina (United States)

Published in SPIE Proceedings Vol. 2980:
Advances in Fluorescence Sensing Technology III
Richard B. Thompson, Editor(s)

© SPIE. Terms of Use
Back to Top