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Proceedings Paper

DNA sequencing by multiple capillaries that form a waveguide
Author(s): Harbans S. Dhadwal; Mark A. Quesada; F. William Studier
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Paper Abstract

A 12-capillary prototype electrophoresis system for DNA sequencing has been constructed. Laser illumination is introduced into an optical waveguide that is formed by an array of individual capillaries that serve both as the optical elements of the periodic array and as the channels containing sieving media for electrophoresis. A theoretical framework and experimental data will be presented to illustrate the viability of this approach.

Paper Details

Date Published: 7 May 1997
PDF: 14 pages
Proc. SPIE 2980, Advances in Fluorescence Sensing Technology III, (7 May 1997); doi: 10.1117/12.273541
Show Author Affiliations
Harbans S. Dhadwal, SUNY/Stony Brook (United States)
Mark A. Quesada, Brookhaven National Lab. (United States)
F. William Studier, Brookhaven National Lab. (United States)


Published in SPIE Proceedings Vol. 2980:
Advances in Fluorescence Sensing Technology III
Richard B. Thompson, Editor(s)

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