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Proceedings Paper

Measurement of the light dosimetry parameters in PDT: definition of a dedicated instrumentation
Author(s): F. Jaffry; V. Louis; Yves Granjon; Francois H. Guillemin; Edouard Yvroud
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Paper Abstract

The PDT uses the LASER characteristics in order to treat locally some types of cancers.Its principle is to irradiate the tumoral zones after the injection of a photosensitizer. Two processes take place during the treatment: one of them is a photochemical process and the other is a photothermal one. The parameters of major interest involved in these processes are the light energy, the oxygen rate in the tumor and the temperature. the aim of the light dosimetry is to optimize the light dose delivered by the LASER in order to enhance the therapeutic yield of the treatment. A sensor dedicated to this task has been studied in our laboratory. Our aim is to perform the measurement of several light dosimetry parameters with a single sensor. These parameters are the light attenuation coefficient, the oxygen saturation and the temperature. The general principle of the instrumentation is based on the backscattering of the light emitted by the optical treatment fiber. The associated instrumentation is composed with three parts: an optical structure, an electronic system and a software for the digital treatment. Our goal is to use this sensor in order to define a general method to extract the different parameters from the single backscattered signal.

Paper Details

Date Published: 8 May 1997
PDF: 7 pages
Proc. SPIE 2972, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy VI, (8 May 1997); doi: 10.1117/12.273500
Show Author Affiliations
F. Jaffry, Ctr. de Recherche en Automatique de Nancy (France)
V. Louis, Ctr. de Recherche en Automatique de Nancy (France)
Yves Granjon, Ctr. de Recherche en Automatique de Nancy (France)
Francois H. Guillemin, Ctr. de Recherche en Automatique de Nancy (France)
Edouard Yvroud, Ctr. de Recherche en Automatique de Nancy (France)


Published in SPIE Proceedings Vol. 2972:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy VI
Thomas J. Dougherty, Editor(s)

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