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Proceedings Paper

ROC study of screen-film mammography and storage phosphor digital mammography: analysis of nonconcordant classifications and implications for the approval of digital mammography systems
Author(s): Matthew T. Freedman; Dorothy Steller Artz; Jacquelyn Hogge; Rebecca A. Zuurbier; Hamid Jafroudi; Shih-Chung Benedict Lo; Seong Ki Mun
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Paper Abstract

A recently completed ROC study of digital mammography using a 100 micron pixel storage phosphor receptor showed that digital mammography and conventional screen film mammography were essentially equivalent in areas under the ROC curve. In this study, there were 24 biopsy proven breast cancer cases, 25 benign biopsy cases and 48 clinically normal breast images each with matched screen film and storage phosphor images. Fifteen of the 24 cancer cases were 10 mm or less in size. Of these 10 presented with microcalcifications as the sign of disease. Six radiologists not involved with the research program and without prior experience with digital mammography and who met qualification criteria under the Mammography Quality Standards Act of 1992 served as readers. This poster looks at the cases in which there was variance between the radiologists ROC classification system for the digital and screen film system in order to analyze case specific discrepancies that may indicate benefits or deficits of the digital system. Aspects of the ROC ratings are also analyzed including an evaluation of the different thresholds used by radiologists on the digital and screen film systems, the distribution of ROC ratings in normal and abnormal cases, the effect of using different gold standards of proof on the results and the effect of substituting an ACR BIRADS category agreement study as proposed by the FDA compared to the ROC study outcome.

Paper Details

Date Published: 16 April 1997
PDF: 11 pages
Proc. SPIE 3036, Medical Imaging 1997: Image Perception, (16 April 1997); doi: 10.1117/12.271303
Show Author Affiliations
Matthew T. Freedman, Georgetown Univ. Medical Ctr. (United States)
Dorothy Steller Artz, Georgetown Univ. Medical Ctr. (United States)
Jacquelyn Hogge, Georgetown Univ. Medical Ctr. (United States)
Rebecca A. Zuurbier, Georgetown Univ. Medical Ctr. (United States)
Hamid Jafroudi, Georgetown Univ. Medical Ctr. (United States)
Shih-Chung Benedict Lo, Georgetown Univ. Medical Ctr. (United States)
Seong Ki Mun, Georgetown Univ. Medical Ctr. (United States)


Published in SPIE Proceedings Vol. 3036:
Medical Imaging 1997: Image Perception
Harold L. Kundel, Editor(s)

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