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Proceedings Paper

Complexity and performance of on-chip biochemical assays
Author(s): Anne R. Kopf-Sill; Theo Nikiforov; Luc J. Bousse; Rob Nagle; J. Wallace Parce
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Paper Abstract

The use of microchips for performing biochemical processes has the potential to reduce reagent use and thus assay costs, increase throughput, and automate complex processes. We are building a multifunctional platform that provides sensing and actuation functions for a variety of microchip- based biochemical and analytical processes. Here we describe recent experiments that include on-chip dilution, reagent mixing, reaction, separation, and detection for important classes of biochemical assays. Issues in chip design and control are discussed.

Paper Details

Date Published: 31 March 1997
PDF: 8 pages
Proc. SPIE 2978, Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications, (31 March 1997); doi: 10.1117/12.269974
Show Author Affiliations
Anne R. Kopf-Sill, Caliper Technologies Corp. (United States)
Theo Nikiforov, Caliper Technologies Corp. (United States)
Luc J. Bousse, Caliper Technologies Corp. (United States)
Rob Nagle, Caliper Technologies Corp. (United States)
J. Wallace Parce, Caliper Technologies Corp. (United States)


Published in SPIE Proceedings Vol. 2978:
Micro- and Nanofabricated Electro-Optical Mechanical Systems for Biomedical and Environmental Applications
Paul Lee Gourley, Editor(s)

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