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Proceedings Paper

Neutron scattering in biology: from isotopic substitution to nuclear spin contrast variation
Author(s): H. B. Stuhrmann
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Paper Abstract

Biological applications of neutron scattering almost entirely rely on methods of isotropic substitution of hydrogen 1H by its heavier isotope 2H. The exchange of water by heavy water D2O has been most widely used for the characterization of the internal structure of complex particles, like viruses, mostly at low resolution. This method is known as contrast variation. A more detailed structural information is obtained when small components of a complex structure have a different isotopic composition. The structural studies on ribsomes are an example which will be discussed here. A further considerable enhancement of the contrast is observed when polarized neutrons are scattered by polarized proton spins.

Paper Details

Date Published: 27 February 1997
PDF: 7 pages
Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); doi: 10.1117/12.267880
Show Author Affiliations
H. B. Stuhrmann, GKSS Forschungszentrum (Germany)


Published in SPIE Proceedings Vol. 2867:
International Conference Neutrons in Research and Industry
George Vourvopoulos, Editor(s)

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