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Proceedings Paper

Portable flow immunosensor for detecting drugs and explosives
Author(s): Anne W. Kusterbeck; Paul R. Gauger; Paul T. Charles
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Paper Abstract

To assist in airport surveillance efforts, a biosensor based on antibody recognition of individual explosives and drugs has been developed at the Naval Research Laboratory. Analysis of samples containing ng/mL levels of the material are completed in under one minute. Immunoassays for the explosives and the five major drugs of abuse are currently available. The intrinsic nature of antigen-antibody binding also provides the unit with an inherently high degree of selectivity. A portable version of the biosensor that can be run by non-technical personnel is also being engineered. The device, including pumps and fluorometer, will be housed on a modified PCMCIA cartridge fitted into a laptop computer. To run assays, a disposable coupon containing the antibody/fluorescent-antigen complex is inserted into the unit and samples are introduced via a sampling port. Results can be viewed in real time or stored on the computer for later data retrieval and analysis.

Paper Details

Date Published: 17 February 1997
PDF: 6 pages
Proc. SPIE 2937, Chemistry- and Biology-Based Technologies for Contraband Detection, (17 February 1997); doi: 10.1117/12.266773
Show Author Affiliations
Anne W. Kusterbeck, Naval Research Lab. (United States)
Paul R. Gauger, Geo-Centers, Inc. (United States)
Paul T. Charles, Naval Research Lab. (United States)


Published in SPIE Proceedings Vol. 2937:
Chemistry- and Biology-Based Technologies for Contraband Detection
Pierre Pilon; Steve Burmeister, Editor(s)

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