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Proceedings Paper

In-vivo measuring of blood-flow changes using diffusing wave correlation techniques
Author(s): Igor Victorovich Meglinski; David A. Boas; Arjun G. Yodh; Britton Chance
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Paper Abstract

We have non-invasively measured in vivo blood flow changes using photon correlation spectroscopy with a simple correlation diffusion model to study and quantify blood flow in the human arm during cuff ischemia. The method utilizes the Doppler broadening of light that arises in a multiply scattering dynamic media, and is also responsive to changes in absorption and scattering coefficients. Our measurements clearly show blood flow changes with cuff pressures, including the hyperemic overshoot after cuff release, that qualitatively agree with the physiological behavior of the cardiovascular system. In this paper, we present our method, results and discuss the clinical relevance of our findings.

Paper Details

Date Published: 11 February 1997
PDF: 8 pages
Proc. SPIE 3053, Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies: International Workshop, (11 February 1997); doi: 10.1117/12.266252
Show Author Affiliations
Igor Victorovich Meglinski, Univ. of Pennsylvania (United States)
Saratov State Univ. (Russia)
David A. Boas, Univ. of Pennsylvania (United States)
Arjun G. Yodh, Univ. of Pennsylvania (United States)
Britton Chance, Univ. of Pennsylvania (United States)


Published in SPIE Proceedings Vol. 3053:
Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies: International Workshop
Valery V. Tuchin, Editor(s)

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