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Proceedings Paper

Photosensitizer for PDT based on phosphonate phthalocyanine derivative
Author(s): Gennadii A. Meerovich; Eugeny A. Lukyanets; Olga A. Yuzhakova; Oleg L. Kaliya; Georgy N. Vorozhtsov; Victor B. Loschenov; Nadezgda L. Torshina; Alexander A. Stratonnikov; Eugenia A. Kogan
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Paper Abstract

It is very important to develop new sensitizer which could be efficiently excited at wavelengths exceeding 685 nm where own tissue absorption can be neglected. We have synthesize water soluble phthalocyanine derivative having phosphonate groups as substituents in macrocycle. New sensitizer efficiently absorbs in spectral range 685 - 710 nm. It exhibits intense fluorescence in range 690 -720 nm. The photodynamic activity of new sensitizer is higher than in the case of sulfonated aluminum phthalocyanine.

Paper Details

Date Published: 4 December 1996
PDF: 5 pages
Proc. SPIE 2924, Photochemotherapy: Photodynamic Therapy and Other Modalities II, (4 December 1996); doi: 10.1117/12.260769
Show Author Affiliations
Gennadii A. Meerovich, General Physics Institute (Russia)
Eugeny A. Lukyanets, NIOPIK Institute of Organic Intermediates and Dyes (Russia)
Olga A. Yuzhakova, NIOPIK Institute of Organic Intermediates and Dyes (Russia)
Oleg L. Kaliya, NIOPIK Institute of Organic Intermediates and Dyes (Russia)
Georgy N. Vorozhtsov, NIOPIK Institute of Organic Intermediates and Dyes (Russia)
Victor B. Loschenov, General Physics Institute (Russia)
Nadezgda L. Torshina, General Physics Institute (Russia)
Alexander A. Stratonnikov, General Physics Institute (Russia)
Eugenia A. Kogan, Moscow Medical Academy (Russia)


Published in SPIE Proceedings Vol. 2924:
Photochemotherapy: Photodynamic Therapy and Other Modalities II
Stanley B. Brown; Benjamin Ehrenberg; Johan Moan, Editor(s)

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