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Proceedings Paper

Endoluminal photodynamic therapy: influence of tissue optical properties on light fluence in the cylindrical diffusing fiber geometry
Author(s): S. Saponaro; B. Farina; Lars H. P. Murrer; Emanuele Pignoli; Raffaella Rizzo; Willem M. Star; Stefano Tomatis; Renato Marchesini
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Paper Abstract

A Monte Carlo model has been developed to simulate the fluence distribution in a fully cylindrical geometry, when a finite linear light source is placed on the axis of a hollow organ during PDT treatment. Height and radius of the cavity, scattering and absorption coefficients, anisotropy factor (g), refractive index of medium and cavity are required as input by the MC code. Data obtained from this model were subsequently compared with experimental results using a tissue simulating phantom. An aqueous solution of Intralipid-10 percent and black ink were used to simulate optical properties. A helium-neon laser, coupled to a cylindrical diffuser was employed as light source. A good agreement between the MC simulations and experimental measurements was found.

Paper Details

Date Published: 5 December 1996
PDF: 10 pages
Proc. SPIE 2923, Laser-Tissue Interaction and Tissue Optics II, (5 December 1996); doi: 10.1117/12.260721
Show Author Affiliations
S. Saponaro, Istituto Nazionale Tumori (Italy)
B. Farina, Istituto Nazionale Tumori (Italy)
Lars H. P. Murrer, Dr. Daniel den Hoed Kliniek (Netherlands)
Emanuele Pignoli, Istituto Nazionale Tumori (Italy)
Raffaella Rizzo, Istituto Nazionale Tumori (Italy)
Willem M. Star, Dr. Daniel den Hoed Kliniek (Netherlands)
Stefano Tomatis, Istituto Nazionale Tumori (Italy)
Renato Marchesini, Istituto Nazionale Tumori (Italy)


Published in SPIE Proceedings Vol. 2923:
Laser-Tissue Interaction and Tissue Optics II
Hansjoerg Albrecht; Guy P. Delacretaz; Thomas H. Meier; Rudolf W. Steiner; Lars Othar Svaasand, Editor(s)

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