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Proceedings Paper

Quantity change in collagen following 830-nm diode laser welding
Author(s): Jing Tang; David O'Callaghan; Simone Rouy; Guilhem Godlewski M.D.; Michel Prudhomme M.D.
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Paper Abstract

The actual mechanism for production of laser welding of tissue is presently unknown, but collagen plays an important role is tissue welded after laser irradiance. The quantity change in collagen extracted from the abdominal aorta of Wistar rats after tissue welding using an 830 nm diode laser was investigated. The collagen contents following repeated pepsin digestion after acetic acid extraction were determined with Sircol collagen assay. Compared with untreated aorta, the collagen content of the treated vessel was obvious decreased immediately after laser irradiation and following an initial increase on day 3, there was a peak at day 10. The results suggest that a part of collagen molecules is denatured by the heat of laser. There is an effect of stimulating collagen synthesis after laser welding with parameters used in this study.

Paper Details

Date Published: 3 December 1996
PDF: 4 pages
Proc. SPIE 2922, Laser Applications in Medicine and Dentistry, (3 December 1996); doi: 10.1117/12.260705
Show Author Affiliations
Jing Tang, Univ. de Montpellier I and INSERM (France)
David O'Callaghan, Univ. de Montpellier I and INSERM (France)
Simone Rouy, Univ. de Montpellier I and INSERM (France)
Guilhem Godlewski M.D., Univ. de Montpellier I and INSERM (France)
Michel Prudhomme M.D., Univ. de Montpellier I and INSERM (France)


Published in SPIE Proceedings Vol. 2922:
Laser Applications in Medicine and Dentistry
Gregory B. Altshuler; Fausto Chiesa; Herbert J. Geschwind M.D.; Raimund Hibst; Neville Krasner M.D.; Frederic Laffitte; Giulio Maira; Reinhard Neumann; Roberto Pini; Hans-Dieter Reidenbach; Andre Roggan; Montserrat Serra I Mila, Editor(s)

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