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Proceedings Paper

Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas
Author(s): Bahman Anvari; B. Samuel Tanenbaum; Thomas E. Milner; Wendy Hoffman; Samireh Said; Cheng-Jen Chang; Lih-Huei L. Liaw; Sol Kimel; J. Stuart Nelson
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Paper Abstract

The clinical objective in laser treatment of hemangiomas is to photocoagulate the dilated cutaneous blood vessels, while at the same time minimizing nonspecific thermal injury to the overlying epidermis. We present an in-vivo experimental procedure, using a chicken comb animal model, and an infrared feedback system to deliver repetitive cryogen spurts during continuous Nd:YAG laser irradiation. Gross and histologic observations are consistent with calculated thicknesses of protected and damaged tissues, and demonstrate the feasibility of inducing spatially selective photocoagulation when using cryogen spray cooling in conjunction with laser irradiation. Experimental observation of epidermal protection in the chicken comb model suggests selective photocoagulation of subsurface targeted blood vessels for successful treatment of hemangiomas can be achieved by repetitive applications of a cryogen spurt during continuous Nd:YAG laser irradiation.

Paper Details

Date Published: 3 December 1996
PDF: 9 pages
Proc. SPIE 2922, Laser Applications in Medicine and Dentistry, (3 December 1996); doi: 10.1117/12.260697
Show Author Affiliations
Bahman Anvari, Beckman Laser Institute and Medical Clinic (United States)
Harvey Mudd College (United States)
B. Samuel Tanenbaum, Harvey Mudd College (United States)
Thomas E. Milner, Beckman Laser Institute and Medical Clinic (United States)
Wendy Hoffman, Univ. of California/Irvine (United States)
Samireh Said, Univ. of California/Irvine (United States)
Cheng-Jen Chang, Chang Gung Memorial Hospital (Taiwan)
Lih-Huei L. Liaw, Beckman Laser Institute and Medical Clinic (United States)
Sol Kimel, Technion--Israel Institute of Technology (Israel)
J. Stuart Nelson, Univ. of California/Irvine (United States)


Published in SPIE Proceedings Vol. 2922:
Laser Applications in Medicine and Dentistry
Gregory B. Altshuler; Fausto Chiesa; Herbert J. Geschwind; Raimund Hibst; Neville Krasner; Frederic Laffitte; Giulio Maira; Reinhard Neumann; Roberto Pini; Hans-Dieter Reidenbach; Andre Roggan; Montserrat Serra I Mila, Editor(s)

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