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Proceedings Paper

Noninvasive NADH measurements for clinical applications
Author(s): Werner Schramm; Wolfgang Hoehne; Herbert G. Stepp; Andreas Leunig
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Paper Abstract

Although NAD/NADH and their spectroscopical characteristics have been well known for a relatively long time, the use of NADH-fluorescence measurements for clinical diagnostics is rather rare up to now Probing the application of a multifiber-NADH-fluorescence-measuring-apparatus in different fields of clinical research and clinical practice, the wide span of applicability is demonstrated. The main purpose of NADH-fluorescence diagnosis is to monitor the well-functioning of the respiratory chain, i.e. the energy metabolic situation of the tissue area probed. As a typical example, the observation of the metabolic state of tissue in transplantation surgery is considered on the one hand and the usefulness of the topological recognition of tumor areas on the other hand.

Paper Details

Date Published: 11 December 1996
PDF: 4 pages
Proc. SPIE 2927, Optical and Imaging Techniques for Biomonitoring II, (11 December 1996); doi: 10.1117/12.260634
Show Author Affiliations
Werner Schramm, Institute of Molecular Pharmacology (Germany)
Wolfgang Hoehne, Institute of Molecular Pharmacology (Germany)
Herbert G. Stepp, Ludwig-Maximilians-Univ. Muenchen (Germany)
Andreas Leunig, Ludwig-Maximilians-Univ. Muenchen (Germany)

Published in SPIE Proceedings Vol. 2927:
Optical and Imaging Techniques for Biomonitoring II
Hans-Jochen Foth; Renato Marchesini; Halina Podbielska, Editor(s)

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