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Proceedings Paper

Clinical effectiveness of low-power laser radiation and functioning of hemosalivatory barrier in patients with rheumatic diseases
Author(s): Natalia D. Gladkova; Alexander B. Karachistov; Lia G. Komarova; Olga P. Alekseeva; Elena A. Grunina
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Paper Abstract

We have estimated the clinical effectiveness of several regimes and ways of low power laser therapy (LT) on the basis of a double 'blind', placebo-controlling randomizing comparative test in 454 patients with rheumatic diseases (RD). LT for RD has a well-expressed placebo effect. The level of clinical effect of LT for RD is not so high. We couldn't achieve 'a considerable improvement' in any cases, 'an improvement' was secured in only 18 percent. LT should be viewed as a symptomatic means, with a primary anesthetic and feebly expressed anti-inflammatory effect, which can not influence the course of the rheumatoid process. Only in 15 percent of patients with RD, a sufficient functioning of hemo-salivary barrier was observed, the latter providing a reserve for adaption mechanism, which leads under the influence of stressor agents of medium strength not only to anesthetic, but also to moderately expressed anti- inflammatory effect.

Paper Details

Date Published: 25 November 1996
PDF: 8 pages
Proc. SPIE 2929, Effects of Low-Power Light on Biological Systems II, (25 November 1996); doi: 10.1117/12.259988
Show Author Affiliations
Natalia D. Gladkova, Institute of Applied Physics (Russia)
Alexander B. Karachistov, Nizhny Novgorod Medical Academy (Russia)
Lia G. Komarova, Nizhny Novgorod Medical Academy (Russia)
Olga P. Alekseeva, Nizhny Novgorod Medical Academy (Russia)
Elena A. Grunina, Nizhny Novgorod Medical Academy (Russia)


Published in SPIE Proceedings Vol. 2929:
Effects of Low-Power Light on Biological Systems II
Giulio Jori; Tiina I. Karu, Editor(s)

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