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Proceedings Paper

Diagnostics of cancer by fiber optic evanescent wave FTIR (FEW-FTIR) spectroscopy
Author(s): Natalia I. Afanasyeva; Sergei F. Kolyakov; Vladilen S. Letokhov; Victor V. Sokolov; George A. Frank
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Paper Abstract

The fiberoptic evanescent wave Fourier transform IR spectroscopy (FEWS) using fiberoptic sensors operated in the attenuated total reflection (ATR) regime in the mid-IR region of the spectrum (4 to 16 micrometer) has recently found application in the diagnostics of biotissues. The silver halide fibers used are non-toxic, non-hygroscopic, flexible and soft and are characterized by a low optical loss. The method allows for non-invasive and rapid (seconds) direct measurements of the spectra of normal and pathological tissues in vitro, ex vivo and in vivo with the aim of express testing of various tumor tissues at the early stages of their development. The method is expected to be further developed for endoscopic and biopsy applications.

Paper Details

Date Published: 26 November 1996
PDF: 4 pages
Proc. SPIE 2928, Biomedical Systems and Technologies, (26 November 1996); doi: 10.1117/12.259954
Show Author Affiliations
Natalia I. Afanasyeva, Institute of Spectroscopy (Russia)
Sergei F. Kolyakov, Institute of Spectroscopy (Russia)
Vladilen S. Letokhov, Institute of Spectroscopy (Russia)
Victor V. Sokolov, P.A. Hertzen Oncology Research Institute (Russia)
George A. Frank, P.A. Hertzen Oncology Research Institute (Russia)

Published in SPIE Proceedings Vol. 2928:
Biomedical Systems and Technologies
Nathan I. Croitoru; Martin Frenz; Terence A. King; Riccardo Pratesi; Anna Maria Verga Scheggi; Stefan Seeger; Otto S. Wolfbeis, Editor(s)

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