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Photon-counting Spectral CT with De-noised Principal Component Analysis (PCA)
Author(s): Huiqiao Xie; Yufei Liu; Thomas Thuering; Wenting Long; Xiangyang Tang
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Paper Abstract

While energy-integration spectral CT with the capability of material decomposition has been providing added value to diagnostic CT imaging in the clinic, photon-counting spectral CT is gaining momentum in research and development, with the potential of overcoming more clinically relevant challenges. In practice, the photon-counting spectral CT provides the opportunity for principal component analysis to effectively extract information from the raw data. However, the principal component analysis in spectral CT may suffer from high noise induced by photon starvation, especially in energy bins at the high energy end. Via phantom and small animal studies, we investigate the feasibility of principal component analysis in photon-counting spectral CT and the benefit that can be offered by de-noising with the Content-Oriented Sparse Representation method.

Paper Details

Date Published: 28 May 2019
PDF: 5 pages
Proc. SPIE 11072, 15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, 1107212 (28 May 2019); doi: 10.1117/12.2534414
Show Author Affiliations
Huiqiao Xie, Emory Univ. School of Medicine (United States)
Yufei Liu, Sinovision Technologies (China)
Thomas Thuering, DECTRIS Ltd. (Switzerland)
Wenting Long, Emory Univ. School of Medicine (United States)
Xiangyang Tang, Emory Univ. School of Medicine (United States)


Published in SPIE Proceedings Vol. 11072:
15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine
Samuel Matej; Scott D. Metzler, Editor(s)

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