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Experimental study on the effect of Coptis chinensis-Scutellaria baicalensis on prevention and treatment of ulcerative colitis and antioxidant capacity
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Paper Abstract

To explore the effect of Coptis chinensis-Scutellaria baicalensis on ulcerative colitis in mice and its antioxidant and anti-inflammatory effects in vitro. Sodium dextran sulfate (DSS) was used to induce acute ulcerative colitis in mice, lipopolysaccharide (LPS) was used to induce cell inflammation model, and ABTS and DPPH models were used to evaluate antioxidant capacity. The results showed that the drug had no significant effect on colitis, but cell experiments in vitro showed that the drug had significant anti-inflammatory effect and could scavenge ABTS and DPPH free radicals. Coptis chinensis-scutellaria baicalensis has anti-inflammatory and anti-oxidative effects.

Paper Details

Date Published: 17 May 2019
PDF: 7 pages
Proc. SPIE 11170, 14th National Conference on Laser Technology and Optoelectronics (LTO 2019), 111702I (17 May 2019); doi: 10.1117/12.2533717
Show Author Affiliations
Jianping Deng, Guangdong Pharmaceutical Univ. (China)
Jinan Univ. (China)
Zicong Wu, Guangdong Pharmaceutical Univ. (China)
Jinan Univ. (China)
Zhenling Zhao, Jinan Univ. (China)
Tong-sheng Chen, South China Normal Univ. (China)
Yi-fei Wang, Jinan Univ. (China)
Zhi-ping Wang, Guangdong Pharmaceutical Univ. (China)
Jinan Univ. (China)


Published in SPIE Proceedings Vol. 11170:
14th National Conference on Laser Technology and Optoelectronics (LTO 2019)
Jianqiang Zhu; Weibiao Chen; Zhenxi Zhang; Minlin Zhong; Pu Wang; Jianrong Qiu, Editor(s)

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