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Evaluation of free radical scavenging and anti-oxidative capacity of vespae nidus-epimedii folium formula
Author(s): Fu-ping Xu; Zi-cong Wu; Tong-sheng Chen; Yi-fei Wang; Zhi-ping Wang
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Paper Abstract

Vespae nidus has been used in traditional Chinese medicine for thousands of years to treat a variety of diseases, including malignant tumors, rheumatoid arthritis, lung diseases, skin disease, digestive and urinary disorders, and dental diseases. As the same, Epimedii folium used to treat kidney-Yang deficiency,impotence and seminal emission, limp wilting sinews and bones, rheumatic arthralgia, Numbness and paralysis, osteoporosis. Vespae nidus-Epimedii folium formula used to treat chronic arthralgia due to Yang deficiency, and painful joints. But the underlying mechanisms by which it exerts therapeutic function have not been thoroughly studied. Cellular damage induced by free-radicals like reactive oxygen species has been implicated in several diseases. Hence naturally anti-oxidant play a vital role in combating these conditions. In this study, The effects of Vespae Nidus nidus-Epimedii folium formula aqueous extract (VEF) on free radical scavenging and anti-oxidative capacity is investigated. By free radical scavenging assays, the IC50 value of VEF were 71.33, 54.07 μg/mL with DPPH, ABTS assay respectively, and 0.161mg ferrous sulfate/1 mg VEF with FRAP assay. These results indicated that the antioxidant properties of VEF hold great potential used as an alternative to more toxic synthetic anti-oxidants as an additive in food, cosmetic and pharmaceutical preparations for the oxidative diseases treatment.

Paper Details

Date Published: 17 May 2019
PDF: 6 pages
Proc. SPIE 11170, 14th National Conference on Laser Technology and Optoelectronics (LTO 2019), 111700E (17 May 2019); doi: 10.1117/12.2531797
Show Author Affiliations
Fu-ping Xu, Univ. of Chinese Medicine (China)
Zi-cong Wu, Guangdong Pharmaceutical Univ. (China)
Jinan Univ. (China)
Tong-sheng Chen, South China Normal Univ. (China)
Yi-fei Wang, Jinan Univ. (China)
Guangzhou Jinan Biomedical Research and Development Ctr. Co., Ltd. (China)
Zhi-ping Wang, Guangdong Pharmaceutical Univ. (China)


Published in SPIE Proceedings Vol. 11170:
14th National Conference on Laser Technology and Optoelectronics (LTO 2019)
Jianqiang Zhu; Weibiao Chen; Zhenxi Zhang; Minlin Zhong; Pu Wang; Jianrong Qiu, Editor(s)

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