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Evaluation of free radical scavenging and anti-oxidative capacity of Guigan longmu Decoction
Author(s): Fu-ping Xu; Zi-cong Wu; Tong-sheng Chen; Yi-fei Wang; Zhi-Ping Wang
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Paper Abstract

Guigan longmu Decoction(GL), take in Zhong-jing Zhang’s Treatise on Exogenous of Febrile Diseases, composed of Cinnamomum cassia Presl(Guizhi), Glycyrrhiza uralensis Fisch.(Gancao), Fossil fragments(Longgu) and Oyster shell(Muli), is a traditional Chinese medicine(TCM) formula and is widely used as a clinically medication formula for its efficiency in improving sleep. But the underlying mechanisms by which it exerts therapeutic function have not been thoroughly studied. Cellular damage induced by free-radicals like reactive oxygen species has been implicated in several diseases. Hence naturally anti-oxidant play a vital role in combating these conditions. In this study, The effects of GL on free radical scavenging and anti-oxidative capacity is investigated. By free radical scavenging assays, the IC50 values of GL were 46.03±1.26, 51.45±0.74 μg/ml with DPPH, ABTS assay respectively, and 0.611 mg ferrous sulfate/1 mg GL with FRAP assay. These results indicated that the antioxidant properties of GL hold great potential used as an alternative to more toxic synthetic anti-oxidants as an additive in food, cosmetic and pharmaceutical preparations for the oxidative diseases treatment.

Paper Details

Date Published: 17 May 2019
PDF: 6 pages
Proc. SPIE 11170, 14th National Conference on Laser Technology and Optoelectronics (LTO 2019), 111700D (17 May 2019); doi: 10.1117/12.2531791
Show Author Affiliations
Fu-ping Xu, Guangdong Provincial Hospital of Chinese Medicine (China)
Zi-cong Wu, Guangdong Pharmaceutical Univ. (China)
Jinan Univ. (China)
Tong-sheng Chen, South China Normal Univ. (China)
MOE Key Lab. of Laser Life Science (China)
Yi-fei Wang, Jinan Univ. (China)
Guangzhou Jinan Biomedical Research and Development Ctr. Co., Ltd. (China)
Zhi-Ping Wang, Guangdong Pharmaceutical Univ. (China)


Published in SPIE Proceedings Vol. 11170:
14th National Conference on Laser Technology and Optoelectronics (LTO 2019)
Jianqiang Zhu; Weibiao Chen; Zhenxi Zhang; Minlin Zhong; Pu Wang; Jianrong Qiu, Editor(s)

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