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Time-domain diffuse correlation spectroscopy quantifies path-length-resolved dynamical properties of a layered turbid media
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Paper Abstract

We apply time-domain diffuse correlation spectroscopy (TD DCS) to quantify dynamics in a two-layer turbid phantom, where the top layer contains purely static, while bottom layer contains only dynamic scatterers. We demonstrate that the standard TD DCS processing is incapable to properly quantify dynamics at short sourcedetector distances (<1 cm) due to strong influence of the static layer. To solve this problem we introduce a novel model accompanied by the numerical noise-correction, which allows to properly recover the autocorrelation decay of the dynamic homogeneous medium hidden by the static turbid layer. Our approach can be thus beneficial for DCS applications in samples with mixed dynamics.

Paper Details

Date Published: 11 July 2019
PDF: 3 pages
Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110740B (11 July 2019); doi: 10.1117/12.2527160
Show Author Affiliations
Saeed Samaei, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)
Dawid Borycki, Institute of Physical Chemistry (Poland)
Michal Kacprzak, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)
Piotr Sawosz, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)
Adam Liebert, Nalecz Institute of Biocybernetics and Biomedical Engineering (Poland)


Published in SPIE Proceedings Vol. 11074:
Diffuse Optical Spectroscopy and Imaging VII
Hamid Dehghani; Heidrun Wabnitz, Editor(s)

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