Share Email Print
cover

Proceedings Paper • new

Optoacoustic angiography of experimental tumors
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Raster-scan optoacoustic angiography at 532 nm wavelength with 50 μm lateral resolution at 2 mm diagnostic depth was used for quantitative characterization of neoangiogenesis in colon cancer models. Vessels of subcutaneously growing murine colon carcinoma (СT26) was imaged from 5th to 13th day of growth. The values of vascular density were calculated from the optoacoustic data. Inhomogeneous distribution of areas with high and low vascularization was demonstrated in the tumors. During tumor development vessel growth from the periphery to the center of the tumor was shown. Increase of vascular density precedes the increase of tumor volume. The obtained results may be important for the investigation of tumor development and for improvement of cancer treatment strategies.

Paper Details

Date Published: 19 July 2019
PDF: 3 pages
Proc. SPIE 11077, Opto-Acoustic Methods and Applications in Biophotonics IV, 1107711 (19 July 2019); doi: 10.1117/12.2527148
Show Author Affiliations
Anna Orlova, Institute of Applied Physics (Russian Federation)
Marina Sirotkina, Privolzhsky Research Medical Univ. (Russian Federation)
Ekaterina Smolina, Institute of Applied Physics (Russian Federation)
Vadim Elagin, Privolzhsky Research Medical Univ. (Russian Federation)
Ilya Turchin, Institute of Applied Physics (Russian Federation)
Pavel Subochev, Institute of Applied Physics (Russian Federation)


Published in SPIE Proceedings Vol. 11077:
Opto-Acoustic Methods and Applications in Biophotonics IV
Vasilis Ntziachristos; Roger Zemp, Editor(s)

© SPIE. Terms of Use
Back to Top