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Doppler imaging of intracellular dynamics in clinical cancer chemotherapy
Author(s): David D. Nolte; John J. Turek; Daniela E. Matei; Shadia Jalal
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Paper Abstract

Biodynamic imaging of chemotherapy response in ex vivo patient biopsies measures changes of intracellular dynamics in response to applied therapeutics. The technique is based on near-IR low-coherence digital holography of Dopplerbroadened light scattering from intracellular dynamics. Three clinical trials of this diagnostic biophotonic technology are nearing completion in esophageal cancer, epithelial ovarian cancer and breast cancer.

Paper Details

Date Published: 19 July 2019
PDF: 3 pages
Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 110730J (19 July 2019); doi: 10.1117/12.2527073
Show Author Affiliations
David D. Nolte, Purdue Univ. (United States)
John J. Turek, Purdue Univ. (United States)
Daniela E. Matei, Feinberg School of Medicine, Northwestern Univ. (United States)
Shadia Jalal, Indiana Univ. School of Medicine (United States)


Published in SPIE Proceedings Vol. 11073:
Clinical and Preclinical Optical Diagnostics II
J. Quincy Brown; Ton G. van Leeuwen, Editor(s)

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