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Pixel-wise modified Beer-Lambert model for intraoperative functional brain mapping
Author(s): Charly Caredda; Laurent Mahieu-Williame; Raphaël Sablong; Michaël Sdika; Jacques Guyotat; Bruno Montcel
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Paper Abstract

A RGB camera and a continuous wave white light illumination is a suitable approach to intraoperatively localize the sensory and motor areas of the patient brain. The analysis of the reflectance spectra through the modified Beer-Lambert law enables us to measure the concentration changes of oxygenated and deoxygenated hemoglobin during the video acquisition. However these concentration changes depend on the wavelength dependent optical mean path length. A manual image segmentation and Monte-Carlo simulations allow us to precisely choose the mean path length in a pixel-wise manner.

Paper Details

Date Published: 19 July 2019
PDF: 5 pages
Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 1107317 (19 July 2019); doi: 10.1117/12.2527045
Show Author Affiliations
Charly Caredda, Univ. de Lyon, INSA-Lyon, Univ. Claude Berndard Lyon 1, UJM-Saint Etienne, CNRS, INSERM (France)
Laurent Mahieu-Williame, Univ. de Lyon, INSA-Lyon, Univ. Claude Berndard Lyon 1, UJM-Saint Etienne, CNRS, INSERM (France)
Raphaël Sablong, Univ. de Lyon, INSA-Lyon, Univ. Claude Berndard Lyon 1, UJM-Saint Etienne, CNRS, INSERM (France)
Michaël Sdika, Univ. de Lyon, INSA-Lyon, Univ. Claude Berndard Lyon 1, UJM-Saint Etienne, CNRS, INSERM (France)
Jacques Guyotat, Hospices Civils de Lyon (France)
Bruno Montcel, Univ. de Lyon, INSA-Lyon, Univ. Claude Berndard Lyon 1, UJM-Saint Etienne, CNRS, INSERM (France)


Published in SPIE Proceedings Vol. 11073:
Clinical and Preclinical Optical Diagnostics II
J. Quincy Brown; Ton G. van Leeuwen, Editor(s)

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