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Monitoring radiofrequency ablation of biological tissue using broadband time-resolved diffuse optical spectroscopy
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Paper Abstract

Radiofrequency ablation (RFA) is minimally invasive thermotherapy, where a heating source is used to target and kill malignant cells in a tissue. While RFA has tremendous potential in the field of oncology, there is also a need for reliable real-time monitoring of this procedure to avoid over or under treatment. In this work, we investigate the use of timeresolved diffuse optical spectroscopy (DOS) to continuously track the change in optical properties during RFA to monitor the process of ablation. The time evolution of the spectra of the optical properties of the tissue undergoing treatment gives deep insights into the structural and constitutional changes occurring during the RFA treatment.

Paper Details

Date Published: 11 July 2019
PDF: 3 pages
Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110742M (11 July 2019); doi: 10.1117/12.2526964
Show Author Affiliations
Pranav Lanka, Politecnico di Milano (Italy)
K. J. Francis, Univ. of Twente (Netherlands)
Hindrik Kruit, Univ. of Twente (Netherlands)
Sanathana Konugolu Venkata Sekar, Politecnico di Milano (Italy)
Andrea Farina, CNR-Istituto di Fotonica e Nanotecnologie (Italy)
Rinaldo Cubeddu, Politecnico di Milano (Italy)
Srirang Manohar, Univ. of Twente (Netherlands)
Antonio Pifferi, Politecnico di Milano (Italy)
CNR-Istituto di Fotonica e Nanotecnologie (Italy)

Published in SPIE Proceedings Vol. 11074:
Diffuse Optical Spectroscopy and Imaging VII
Hamid Dehghani; Heidrun Wabnitz, Editor(s)

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