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Microlaser-based contractility sensing in single cardiomyocytes and whole hearts
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Paper Abstract

Microscopic whispering gallery mode lasers detect minute changes in cellular refractive index inside individual cardiac cells and in live zebrafish. We show that these signals encode cardiac contractility that can be used for intravital sensing.

Paper Details

Date Published: 22 July 2019
PDF: 3 pages
Proc. SPIE 11075, Novel Biophotonics Techniques and Applications V, 110750C (22 July 2019); doi: 10.1117/12.2526955
Show Author Affiliations
Marcel Schubert, Univ. of St. Andrews (United Kingdom)
Lewis Woolfson, Univ. of St. Andrews (United Kingdom)
Isla R. M. Barnard, Univ. of St. Andrews (United Kingdom)
Andrew Morton, Univ. of St. Andrews (United Kingdom)
Becky Casement, Univ. of St. Andrews (United Kingdom)
Gavin B. Robertson, Univ. of St. Andrews (United Kingdom)
Gareth B. Miles, Univ. of St. Andrews (United Kingdom)
Samantha J. Pitt, Univ. of St. Andrews (United Kingdom)
Carl S. Tucker, The Queen’s Medical Research Institute, The Univ. of Edinburgh (United Kingdom)
Malte C. Gather, Univ. of St. Andrews (United Kingdom)


Published in SPIE Proceedings Vol. 11075:
Novel Biophotonics Techniques and Applications V
Arjen Amelink; Seemantini K. Nadkarni, Editor(s)

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