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Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery
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Paper Abstract

The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.

Paper Details

Date Published: 22 July 2019
PDF: 5 pages
Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791C (22 July 2019); doi: 10.1117/12.2526747
Show Author Affiliations
Ksenia Kandurova, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Elena Potapova, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Valery Shupletsov, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Igor Kozlov, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Evgeniya Seryogina, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Viktor Dremin, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Univ. of Oulu (Finland)
Evgeny Zherebtsov, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Univ. of Oulu (Finland)
Alexander Alekseyev M.D., Orel State Univ. named after I.S. Turgenev (Russian Federation)
Andrian Mamoshin M.D., Orel State Univ. named after I.S. Turgenev (Russian Federation)
Orel Regional Clinical Hospital (Russian Federation)
Andrey Dunaev, Orel State Univ. named after I.S. Turgenev (Russian Federation)


Published in SPIE Proceedings Vol. 11079:
Medical Laser Applications and Laser-Tissue Interactions IX
Lothar D. Lilge; Carsten M. Philipp, Editor(s)

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