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Methylene blue as a photosensitizer in the photodynamic therapy of breast cancer cell lines
Author(s): JC Atenco-Cuautle; T. Spezzia-Mazzocco; R. Ramos-Garcia; JC Ramirez-San-Juan; J. Ramirez-Ramirez; MG Delgado-Lopez
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Paper Abstract

We compared MB-PDT effect on two breast cancer cell lines: MDA-MB-231 from a triple negative adenocarcinoma, and T47D from a ductal cell tumor of woman. Methylene blue concentrations at 5, 10 and 20 μM and red light doses of 20, 40 and 60 J/cm2 were employed. Cell viability was evaluated with the MTT test, obtaining around 80% of inhibition with 20 μM and 60 J/cm2 of light dose.

Paper Details

Date Published: 7 August 2019
PDF: 4 pages
Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 11070A0 (7 August 2019); doi: 10.1117/12.2525454
Show Author Affiliations
JC Atenco-Cuautle, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
T. Spezzia-Mazzocco, CÁTEDRA-CONACYT-Instituto Nacional de Astrofisica (Mexico)
R. Ramos-Garcia, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
JC Ramirez-San-Juan, Instituto Nacional de Astrofísica, Óptica y Electrónica (Mexico)
J. Ramirez-Ramirez, Instituto Nacional de Astrofisica, Optica y Electronica (Mexico)
MG Delgado-Lopez, Ctr. de Investigacion Biomedica de Oriente (Mexico)


Published in SPIE Proceedings Vol. 11070:
17th International Photodynamic Association World Congress
Tayyaba Hasan, Editor(s)

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