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5-Aminolevulinic acid photodynamic therapy: an effective treatment modality for female precancerous lesions: experience of a single center
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Paper Abstract

A total of 62 female patients who underwent ALA-PDT at the Gynecology Department of Henan Province People's Hospital in 2018 were retrospectively assessed. Lesions included 24 case of LSIL, 13 case of HSIL, 12 case of VAIN, 2 case of VIN and 11 case of VL. Three-six sessions of ALA-PDT were carried out at intervals of ten days. The treatment efficacy was evaluated by colposcopy, TCT and HPV dectection. After one month follow-up, The effective rate of LSI, HSIL, VAIN, VIN and VL were 70.8%, 84.6%, 83.3%, 100% and 100%. After three month follow-up, The effective rate of LSIL, HSIL, VAIN, VIN and VL were 83.3%, 92.3%, 83.3%, 100% and 100%. After six month follow-up, The effective rate of LSIL, HSIL, VAIN, VIN and VL were 87.5%, 92.3%, 91.7%, 100% and 100%. Our experience show that ALA-PDT is an effective treatment modality for female genital precancerous lesions. Keywords: 5-aminolevulinic acid photodynamic therapy, Low-grade cervical squamous intraepithelial lesions,

Paper Details

Date Published: 7 August 2019
PDF: 6 pages
Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 1107023 (7 August 2019); doi: 10.1117/12.2525244
Show Author Affiliations
Guangzhi Liu, Henan Provincial People’s Hospital (China)
People's Hospital of Zhengzhou Univ. (China)
Xiaoli Lu, Henan Provincial People’s Hospital of Henan Univ. (China)
Liyun Yang, Henan Provincial People’s Hospital (China)
Guiqin Chen, Henan Provincial People’s Hospital (China)
Lenan Cheng, Henan Provincial People’s Hospital of Henan Univ. (China)
Bing Mao, Henan Provincial People’s Hospital (China)
Ziyi Zhao, Jilin Univ. (China)
QiuYun Yang, Henan Provincial People's Hospital (China)
Henan Provincial People’s Hospital of Henan Univ. (China)


Published in SPIE Proceedings Vol. 11070:
17th International Photodynamic Association World Congress
Tayyaba Hasan, Editor(s)

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