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Towards poly(D,L-lactic acid)-based biodegradable and biocompatible polymer optical fiber
Author(s): Agnieszka Gierej; Maxime Vagenende; Adam Filipkowski; Bartlomiej Siwicki; Ryszard Buczynski; Hugo Thienpont; Sandra Van Vlierberghe; Thomas Geernaert; Peter Dubruel; Francis Berghmans
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Paper Abstract

We demonstrate a biodegradable and biocompatible unclad optical fiber made from poly(D,L-lactic acid) (PDLLA), which is a well-known and commercially available amorphous polyester. We first deal with the chemical and optical characterization of the bulk polymer material and we report on the influence of the processing on the molecular weight and thermal properties of the polymer, during both the preform preparation and the fiber drawing process. We then proceed to the optical characterization based on spectral attenuation measurements using the cutback method and dispersion measurements. We also determine the thermo-optic coefficient. Finally, we confirm the in vitro degradation in phosphate buffered saline (PBS) of our PDLLA fibers. From the results and considering that PDLLA is an FDAregulated material, we anticipate that our optical fibers are valid candidates for medical applications involving in vivo light delivery, such as for example photodynamic therapy.

Paper Details

Date Published: 15 April 2019
PDF: 9 pages
Proc. SPIE 11029, Micro-structured and Specialty Optical Fibres VI, 110290K (15 April 2019); doi: 10.1117/12.2524698
Show Author Affiliations
Agnieszka Gierej, Vrije Univ. Brussel (Belgium)
Univ. Gent (Belgium)
Maxime Vagenende, Vrije Univ. Brussel (Belgium)
Univ. Gent (Belgium)
Adam Filipkowski, Institute of Electronic Materials Technology (Poland)
Bartlomiej Siwicki, Institute of Electronic Materials Technology (Poland)
Ryszard Buczynski, Institute of Electronic Materials Technology (Poland)
Hugo Thienpont, Vrije Univ. Brussel (Belgium)
Sandra Van Vlierberghe, Vrije Univ. Brussel (Belgium)
Univ. Gent (Belgium)
Thomas Geernaert, Vrije Univ. Brussel (Belgium)
Peter Dubruel, Univ. Gent (Belgium)
Francis Berghmans, Vrije Univ. Brussel (Belgium)


Published in SPIE Proceedings Vol. 11029:
Micro-structured and Specialty Optical Fibres VI
Kyriacos Kalli; Alexis Mendez; Pavel Peterka, Editor(s)

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