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Proceedings Paper

Effect of hyperthemia induced by Nd:YAG laser and photodynamic therapy by Ar+ laser radiation in combination on the transplanted tumor in CM mice
Author(s): Xiaoyuan Li; Runchu Tan; Jishi Li; Hongmin Shi
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Paper Abstract

The present paper reports the effect of hyperthermia (HT) induced by Nd:YAG laser and photodynamic therapy (PDT) by AR+ laser radiation in combination on the transplanted sarcoma 180 in CM mice. Tumor-bearing mice were divided into four groups: A) control group, B) HT group, C) PDT group and D) PDT followed by HT group. HT was induced by Nd:YAG laser radiation and the temperature at tumor edge was control at 43 degrees C for 30 minutes. Tumor-bearing mice of group C and D were given an i.p. injection of HpD 24 hours prior to AR+ laser radiation. The experiments show significant increases in inhibition rates against the S-180 in CM mice by the HT and PDT combination, compared to those by either HT or PDT alone. With that of Group D being the lowest, the DNA contents of tumor cells in the four groups are of statistical significance too. These results suggest the combination of HT induced by Nd:YAG and PDT by Ar+ laser radiation may become a new method of tumor treatment.

Paper Details

Date Published: 23 September 1996
PDF: 6 pages
Proc. SPIE 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment, (23 September 1996); doi: 10.1117/12.251958
Show Author Affiliations
Xiaoyuan Li, Sun Yat-sen Univ. of Medical Sciences (China)
Runchu Tan, Sun Yat-sen Univ. of Medical Sciences (China)
Jishi Li, Sun Yat-sen Univ. of Medical Sciences (China)
Hongmin Shi, Sun Yat-sen Univ. of Medical Sciences (China)


Published in SPIE Proceedings Vol. 2887:
Lasers in Medicine and Dentistry: Diagnostics and Treatment
Brij M. Khorana; Junheng Li; Michail M. Pankratov, Editor(s)

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