Share Email Print
cover

Proceedings Paper • new

Fiber-enhanced Raman spectroscopy as a tool for an early detection of Alzheimer's disease biomarkers
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Alzheimer’s disease (AD) is an irreversible progressive disease that damages the brain cell and affects the cognitive abilities. Hence an early detection of AD biomarkers is vital for the drug treatment. Considering this, we developed a sensitive and reliable sensing tool based on fiber-enhanced Raman spectroscopic technique for the detection of AD biomarkers. The fiber-enhanced Raman measurements were performed using a hollow core photonic crystal fiber, and a comparison of Raman spectra of samples in a conventional cuvette and with the fiber was carried out. The results showed a high enhancement of Raman signal of samples measured with a fiber compared to the measurements carried out in the cuvette.

Paper Details

Date Published: 27 February 2019
PDF: 6 pages
Proc. SPIE 10872, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIX, 1087211 (27 February 2019); doi: 10.1117/12.2516545
Show Author Affiliations
P. J. Eravuchira, Tel Aviv Univ. (Israel)
M. Banchelli, Istituto di Fisica Applicata "Nello Carrara" (Italy)
C. D'Andrea, Istituto di Fisica Applicata "Nello Carrara" (Italy)
M. De Angelis, Istituto di Fisica Applicata "Nello Carrara" (Italy)
P. Matteini, Istituto di Fisica Applicata "Nello Carrara" (Italy)
I. Gannot, Tel Aviv Univ. (Israel)


Published in SPIE Proceedings Vol. 10872:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIX
Israel Gannot, Editor(s)

© SPIE. Terms of Use
Back to Top