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Minimally invasive intraventricular ultrasound: design and instrumentation towards a miniaturized ultrasound-guided focused ultrasound probe
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Paper Abstract

Neurosurgery typically requires craniectomy and meticulous dissection to achieve sufficient exposure for subsequent surgical intervention. This highly invasive process requires hours of operating time, long recovery periods and leaves patients with visible surgical scars. Non-invasive high-intensity focused ultrasound (HIFU) has shown some promise yet remains challenged by the attenuation of ultrasonic waves while passing through the skull. Consequently, the clinical impact of this technology remains limited, particularly in the treatment of neuro-oncology. In order to compensate for acoustic attenuation, excessive use of power for HIFU devices has been investigated, although it is undesirable from a regulatory and patient safety standpoint. Here, we report the design and development of a novel HIFU device prototype for neurologic lesion ablation. This device concept is envisioned to access the ventricular space via a minimally invasive ventriculostomy, allowing ultrasound to reach targets deep in the brain, while eliminating the need for high power to penetrate the skull.

Paper Details

Date Published: 8 March 2019
PDF: 9 pages
Proc. SPIE 10951, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling, 109512Y (8 March 2019); doi: 10.1117/12.2513150
Show Author Affiliations
Micah Belzberg, Johns Hopkins Univ. (United States)
Francisco Chavez, Sonic Concepts, Inc. (United States)
Kah Timothy Xiong, Sonic Concepts, Inc. (United States)
Kyle Morrison, Sonic Concepts, Inc. (United States)
Nao Gamo, Johns Hopkins Univ. (United States)
Stephen Restaino, Maryland Development Ctr. (United States)
Rajiv Iyer, Johns Hopkins Univ. (United States)
Mari Groves, Johns Hopkins Univ. (United States)
Nitish Thakor, Johns Hopkins Univ. (United States)
Henry Brem, Johns Hopkins Univ. (United States)
Alan Cohen, Johns Hopkins Univ. (United States)
Amir Manbachi, Johns Hopkins Univ. (United States)
Johns Hopkins Armstrong Institute for Patient Safety and Quality (United States)


Published in SPIE Proceedings Vol. 10951:
Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling
Baowei Fei; Cristian A. Linte, Editor(s)

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