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A combined deep-learning approach to fully automatic left ventricle segmentation in cardiac magnetic resonance imaging
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Paper Abstract

In clinical practice, cardiac magnetic resonance imaging (CMR) is considered the gold-standard imaging modality for the evaluation of function and structure of the left ventricle (LV). However, the quantification of LV parameters in all frames, even when performed by experienced radiologists, is very time consuming mainly due to the inhomogeneity of cardiac structures within each image, the variability of the cardiac structures across subjects and the complicated global/regional temporal deformation of the myocardium during the cardiac cycle. In this work, we employed a combination of two convolutional neural networks (CNN) to develop a fully automatic LV segmentation method for Short Axis CMR datasets. The first CNN defines the region of interest (ROI) of the cardiac chambers based on You Only Look Once (YOLO) network. The output of YOLO net is used to filter the image and feed the second CNN, based on UNet network, which segments the myocardium and the blood pool. The method was validated in CMR exams of 59 individuals from an institutional clinical protocol. Segmentation results, evaluated by metrics Percentage of Good Contours, Dice Index and Average Perpendicular distance, were 98,59% ± 4,28%, 0,93 ± 0,06 and 0,72 mm ± 0,62 mm, respectively, for the LV epicardium, and 94,98% ± 14,04%, 0,86 ± 0,13 and 1,19 mm ± 1,29 mm, respectively, for the LV endocardium. The combination of two CNNs demonstrated good performance in terms of the evaluated metrics when compared to literature results.

Paper Details

Date Published: 15 March 2019
PDF: 8 pages
Proc. SPIE 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging, 109531Y (15 March 2019); doi: 10.1117/12.2512895
Show Author Affiliations
Ramon A. Moreno, Univ. of Sao Paulo Medical School (Brazil)
Marina F. S. de Sá Rebelo, Univ. of Sao Paulo Medical School (Brazil)
Talles Carvalho, Univ. of Sao Paulo Medical School (Brazil)
Antonildes N. Assunção, Univ. of Sao Paulo Medical School (Brazil)
Roberto N. Dantas, Univ. of Sao Paulo Medical School (Brazil)
Renata do Val, Univ. of Sao Paulo Medical School (Brazil)
Angela S. Marin, Canon Medical Systems do Brasil (Brazil)
Adriano Bordignom, Canon Medical Systems do Brasil (Brazil)
Cesar H. Nomura, Univ. of Sao Paulo Medical School (Brazil)
Marco A. Gutierrez, Univ. of Sao Paulo Medical School (Brazil)


Published in SPIE Proceedings Vol. 10953:
Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

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