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Multiband terahertz imaging simulation of skin using freezing to enhance penetration depth
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Paper Abstract

The Terahertz (THz) frequency region of the electromagnetic spectrum is defined as radiation of 0.1 to 10.0 x 1012 Hz. A unique feature of the 0.1 to 2.0 THz frequency band is that there is a high disparity between liquid water and ice absorption, with ice being 100 times more permeable to THz radiation. The high absorption by liquid water limits the deployment of 0.1 to 2.0 THz band for imaging and therapeutics to 0.2-0.3 mm in soft tissues. By freezing tissue, however, an imaging depth of 5.0 mm is achievable. Computational finite difference time domain (FDTD) modelling was undertaken using realistic tissue phantoms to explore this enhanced depth for imaging of frozen skin lesions such as melanomas. The computational modeling confirms that there is adequate contrast between normal frozen skin and pathological lesions. The imaging is enhanced by sampling the frozen tissue at both 0.45 and 1.00 THz. A method of analysing the data in a simplified, systematic way is introduced by dividing the returning signal into time regions and comparing their relative intensity. The concept will be developed into a “THz eye”, where the differences in THz absorption and refraction of tissues between individual THz frequencies are exploited for superior imaging.

Paper Details

Date Published: 1 March 2019
PDF: 8 pages
Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109483S (1 March 2019); doi: 10.1117/12.2512342
Show Author Affiliations
Zoltan Vilagosh M.D., Swinburne Univ. of Technology (Australia)
Australian Ctr. for Electromagnetic Bioeffects Research (Australia)
Alireza Lajeverdiour, Swinburne Univ. of Technology (Australia)
Australian Ctr. for Electromagnetic Bioeffects Research (Australia)
Andrew W. Wood, Swinburne Univ. of Technology (Australia)
Australian Ctr. for Electromagnetic Bioeffects Research (Australia)


Published in SPIE Proceedings Vol. 10948:
Medical Imaging 2019: Physics of Medical Imaging
Taly Gilat Schmidt; Guang-Hong Chen; Hilde Bosmans, Editor(s)

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