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Scanning, registration, and fiber estimation of rabbit hearts using micro-focus and refraction-contrast x-ray CT
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Paper Abstract

High-resolution cardiac imaging and fiber analysis methods are desired for deeper understanding cardiac anatomy. Although refraction-contrast X-ray CT (RCT) has high contrast for soft tissues, its scanning cost is very high. On the other hand, micro-focus X-ray CT (μCT) is a modality that is commercially available with lower cost, but its contrast for soft tissue is not as high as RCT. To investigate the efficacy of μCT for fiber analysis, we scanned a common rabbit heart with both modalities with our original protocol of preparing materials, and compared their image-based analysis results. Their results were very similar, with correlation coefficient of 0.95. We confirmed that µCT volumes prepared by our protocol are useful for fiber analysis as well as RCT.

Paper Details

Date Published: 15 March 2019
PDF: 12 pages
Proc. SPIE 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging, 109531I (15 March 2019); doi: 10.1117/12.2512145
Show Author Affiliations
Hirohisa Oda, Nagoya Univ. (Japan)
Holger R. Roth, Nagoya Univ. (Japan)
Takaaki Sugino, Nagoya Univ. (Japan)
Naoki Sunaguchi, Nagoya Univ. (Japan)
Noriko Usami, Nagoya Univ. (Japan)
Masahiro Oda, Nagoya Univ. (Japan)
Daisuke Shimao, Hokkaido Univ. of Science (Japan)
Shu Ichihara, Nagoya Medical Ctr. (Japan)
Tetsuya Yuasa, Yamagata Univ. (Japan)
Masami Ando, Tokyo Univ. of Science (Japan)
Toshiaki Akita, Nagoya Univ. (Japan)
Yuji Narita, Nagoya Univ. (Japan)
Kensaku Mori, Nagoya Univ. (Japan)
National Institute of Informatics (Japan)


Published in SPIE Proceedings Vol. 10953:
Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

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