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Determining elastic contrast in tissue-mimicking phantoms using frequency resolved photoacoustic imaging
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Paper Abstract

Tissue elasticity is an important biomarker for early prediction of diseases, and elastography methods have been developed for several modalities. In practice, photoacoustic imaging (PAI) provides information about the optical properties of deep-seated tissue based on an ultrasonic readout. In this study, we demonstrate the use of PAI to measure tissue elasticity through high frequency acquisitions. The method was tested using tissue mimicking agar phantoms and transducers of different frequencies. The results show that elastic contrast can be recovered from PA signals only using high-frequency transducers, given significant differences of elasticity between the imaging target and background.

Paper Details

Date Published: 27 February 2019
PDF: 5 pages
Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108782M (27 February 2019); doi: 10.1117/12.2511682
Show Author Affiliations
Subhamoy Mandal, German Cancer Research Ctr. (Germany)
Anjali Thomas, Indian Institute of Science Education and Research Thiruvananthapuram (India)
Mayanglambam Suheshkumar Singh, Indian Institute of Science Education and Research Thiruvananthapuram (India)
Dorde Komljenovic, German Cancer Research Ctr. (Germany)


Published in SPIE Proceedings Vol. 10878:
Photons Plus Ultrasound: Imaging and Sensing 2019
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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